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	<title>Health and Prostate &#187; Drugs: Antibiotics</title>
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	<description>Benign Prostatic Hyperplasia - Prostate Cancer - Prostatitis</description>
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		<title>Fluoroquinolone (Quinolone) antibiotics. Clinical Uses. Part 2</title>
		<link>http://healthandprostate.com/drugs-antibiotics/fluoroquinolone-quinolone-antibiotics-clinical-uses-part-2</link>
		<comments>http://healthandprostate.com/drugs-antibiotics/fluoroquinolone-quinolone-antibiotics-clinical-uses-part-2#comments</comments>
		<pubDate>Fri, 04 Dec 2009 08:26:58 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Drugs: Antibiotics]]></category>
		<category><![CDATA[Cipro]]></category>
		<category><![CDATA[Ciprofloxacin]]></category>
		<category><![CDATA[Norfloxacin]]></category>
		<category><![CDATA[Ofloxacin]]></category>
		<category><![CDATA[Sulfamethoxazole]]></category>
		<category><![CDATA[Trimethoprim]]></category>

		<guid isPermaLink="false">http://healthandprostate.com/?p=147</guid>
		<description><![CDATA[Prostatitis Fluoroquinolones have been shown to penetrate into prostatic tissue in concentrations approaching or exceeding by severalfold those in serum (see preceding section). In the only comparative study, when each drug was given for 4 to 6 weeks, norfloxacin was shown to be more effective (P = 0.) than trimethoprim-sulfamethoxazole (TMP-SMX) for therapy of chronic bacterial prostatitis caused predominantly by E. coli. In two open studies also using prolonged therapy, norfloxacin and ciprofloxacin appeared to eradicate E. coli prostatitis in 85 to 92% of patients followed for at least 4 to 6 weeks after completion of therapy. Lower rates of eradication by ciprofloxacin have been associated with therapy given for only 2 weeks and with prostatitis caused by bacteria other than E. coli, including P. aeruginosa and enterococci. Pefloxacin has been reported to be effective in 21 of 31 cases (68%) of chronic prostatitis, with two of eight failures associated with the development of resistance. Acute prostatitis caused predominantly by enteric gram-negative bacilli was also cured at 7 months follow-up Read more [...]]]></description>
			<content:encoded><![CDATA[Prostatitis
Fluoroquinolones have been shown to penetrate into prostatic tissue in concentrations approaching or exceeding by severalfold those in serum (see preceding section). In the only comparative study, when each drug was given for 4 to 6 weeks, norfloxacin was shown to be more effective (P = 0.) than trimethoprim-sulfamethoxazole (TMP-SMX) for therapy of chronic bacterial prostatitis caused predominantly by E. coli. In two open studies also using prolonged therapy, norfloxacin and ciprofloxacin appeared to eradicate E. coli prostatitis in 85 to 92% of patients followed for at least 4 to 6 weeks after completion of therapy. Lower rates of eradication by ciprofloxacin have been associated with therapy given for only 2 weeks and with prostatitis caused by bacteria other than E. coli, including P. aeruginosa and enterococci. Pefloxacin has been reported to be effective in 21 of 31 cases (68%) of chronic prostatitis, with two of eight failures associated with the development of resistance. Acute prostatitis caused predominantly by enteric gram-negative bacilli was also cured at 7 months follow-up <a href="http://healthandprostate.com/drugs-antibiotics/fluoroquinolone-quinolone-antibiotics-clinical-uses-part-2" class="more-link">Read more [...]</a>]]></content:encoded>
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		<item>
		<title>Fluoroquinolone (Quinolone) antibiotics. Clinical Uses. Part 1</title>
		<link>http://healthandprostate.com/drugs-antibiotics/fluoroquinolone-quinolone-antibiotics-clinical-uses-part-1</link>
		<comments>http://healthandprostate.com/drugs-antibiotics/fluoroquinolone-quinolone-antibiotics-clinical-uses-part-1#comments</comments>
		<pubDate>Fri, 04 Dec 2009 08:25:32 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Drugs: Antibiotics]]></category>
		<category><![CDATA[Amoxicillin]]></category>
		<category><![CDATA[Cephalexin]]></category>
		<category><![CDATA[Cipro]]></category>
		<category><![CDATA[Ciprofloxacin]]></category>
		<category><![CDATA[Nalidixic acid]]></category>
		<category><![CDATA[Norfloxacin]]></category>
		<category><![CDATA[Ofloxacin]]></category>
		<category><![CDATA[Sulfamethoxazole]]></category>
		<category><![CDATA[Trimethoprim]]></category>

		<guid isPermaLink="false">http://healthandprostate.com/?p=143</guid>
		<description><![CDATA[Urinary Tract Infections Many of the newer fluoroquinolones achieve high concentrations in human urine (see preceding section). Although the antimicrobial activities of these agents are diminished in the presence of urine, urinary drug concentrations for most agents substantially exceed the minimum inhibitory concentrations (MICs) for both gram-negative and gram-positive urinary tract pathogens, including members of the Enterobacteriaceae, P. aeruginosa, enterococci, and Staphylococcus saprophyticus. Of the newer fluoroquinolones, norfloxacin and ciprofloxacin have been studied most extensively. Studies with norfloxacin and ciprofloxacin have been reviewed recently. In the two largest randomized studies of uncomplicated urinary tract infections comparing therapy with norfloxacin (400 mg given orally twice daily for 3 to 7 days) and that with trimethoprim-sulfamethoxazole (TMP-SMX), eradication of bacteriuria was significantly higher after treatment with norfloxacin in a double-blind randomized study or comparable in the two groups. Similar results were seen in a large number of other comparative Read more [...]]]></description>
			<content:encoded><![CDATA[Urinary Tract Infections
Many of the newer fluoroquinolones achieve high concentrations in human urine (see preceding section). Although the antimicrobial activities of these agents are diminished in the presence of urine, urinary drug concentrations for most agents substantially exceed the minimum inhibitory concentrations (MICs) for both gram-negative and gram-positive urinary tract pathogens, including members of the Enterobacteriaceae, P. aeruginosa, enterococci, and Staphylococcus saprophyticus.

Of the newer fluoroquinolones, norfloxacin and ciprofloxacin have been studied most extensively. Studies with norfloxacin and ciprofloxacin have been reviewed recently. In the two largest randomized studies of uncomplicated urinary tract infections comparing therapy with norfloxacin (400 mg given orally twice daily for 3 to 7 days) and that with trimethoprim-sulfamethoxazole (TMP-SMX), eradication of bacteriuria was significantly higher after treatment with norfloxacin in a double-blind randomized study or comparable in the two groups. Similar results were seen in a large number of other comparative <a href="http://healthandprostate.com/drugs-antibiotics/fluoroquinolone-quinolone-antibiotics-clinical-uses-part-1" class="more-link">Read more [...]</a>]]></content:encoded>
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