Benign Prostatic Hyperplasia – Prostate Cancer – Prostatitis

Silodosin

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Drug Nomenclature

Date of monograph revision: 14-Jun-2006; 28-Jun-2006
Synonyms: KMD-3213
INN: Silodosin [rINN (en)]
INN: Silodosina [rINN (es)]
INN: Silodosine [rINN (fr)]
INN: Silodosinum [rINN (la)]
INN: Сильодозин [rINN (ru)]
Chemical name: (-)-1-(3-Hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carboxamide
Molecular formula: C25H32F3N3O4 =495.5
CAS: 160970-54-7

Profile

Silodosin is an alpha1-adrenoceptor blocker that is reported to be selective for the alpha1A-adrenoceptor subtype. It is used orally in benign prostatic hyperplasia to relieve symptoms of urinary obstruction.

Proprietary Preparations

Japan: Urief

USA: Rapaflo

 
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