Terazosin
Indications mild to moderate hypertension (see notes above); benign prostatic hyperplasia
Cautions first dose may cause collapse due to hypotension (within 30-90 minutes, therefore should be taken on retiring to bed) (may also occur with rapid dose increase); pregnancy; interactions: Appendix 1 (alpha-blockers)
Driving May affect performance of skilled tasks e.g. driving
Side-effects also drowsiness, dizziness, lack of energy, peripheral oedema; urinary frequency and priapism reported
Dose
• Hypertension, 1 mg at bedtime (compliance with bedtime dose important, see Cautions); dose doubled after 7 days if necessary; usual maintenance dose 2-10 mg once daily; more than 20 mg daily rarely improves efficacy
Terazosin (Non-proprietary)
Tablets, terazosin (as hydro chloride) 2 mg, net price 28-tab pack = £2.34; 5 mg, 28-tab pack = £2.78; 10 mg, 28-tab pack = £7.06. Counselling, initial dose, driving
Hytrin® (Amdipharm)
Tablets, terazosin (as hydrochloride) 2 mg (yellow), net price 28-tab pack = £2.29; 5 mg (tan), 28-tab pack = £4.29; 10 mg (blue), 28-tab pack = £8.57; starter pack (for hypertension) of 7 x 1- mg tabs with 21 x 2- mg tabs = £13.00. Counselling, initial dose, driving
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