Diagram of the human androgen receptor gene

Posted by admin on December 22nd, 2009 No Comments

Schematic diagram of the human androgen receptor gene

Black areas = trans-activation domains; P = proline directed phosphorylated Ser residues; HSP = heat shock protein; pKC = protein kinase C; pKA = protein kinase A; MAPK = mitogen-activated protein kinase; DNA-Dep Kin = DNA-dependent kinase; Ser-Pro = serine-proline directed kinase; Cas-Kin II = casein kinase II.

Adapted from Wiener et al., MacLean et al., Blok et al., and Zhou et al.

Effects of tissue localization of the androgen receptor on differentiation of the urogenital sinus
[/caption] Epithelium and stroma from the urogenital sinuses of wild-type (androgen-receptor positive) or Tfm (androgen-receptor negative) mice were recombined and grafted under the renal capsule. Prostatic epithelium ...
Comparison of the gross anatomy of the human and rat prostate
Comparison of the gross anatomy of the human (left) and rat (right) prostate
Effects of tissue localization of the androgen receptor on differentiation of the urogenital sinus (UGS)

PZ = peripheral zone; CZ = central zone; TZ = transition zone; fm = anterior fibromuscular stroma; UD = distal urethra; UP = proximal urethral segment; E = ...

Diagnostic events for prostate cancer

[/caption] Diagnostic events (in squares) in the sequence of screening and follow-up for prostate cancer. The size and darkness of the curved arrows indicate the current knowledge regarding diagnostic tools. Block arrows indicate the function of diagnostic ...

Estimated cancer deaths in 10 leading sites (United States)

Estimated cancer deaths in 10 leading sites by gender, United States

Diagnostic events for prostate cancer

Excludes basal and squamous cell skin cancerand carcinoma in situ except bladder. From Landis S H, Murray T, Bolden S, Wingo P A. Cancer Statistics, 1998. CA Cancer J Clin ...

Combined Androgen Blockade Overview. Combined androgen blockade (CAB)—sometimes called androgen -deprivation therapy—is the simultaneous administration of an LHRH analogue and an antiandrogen. A huge number of randomized, controlled trials have been undertaken to assess the benefit of adding an antiandrogen to LHRH therapy. Mechanism Of Action. The individual ...

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