ESTRAMUSTINE
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ESTRAMUSTINE
(ess-tra-MUSS-teen)
Other Names for this Medication: Emcyt, Estracit(Brand Names)
Appearance
White capsules containing 140mg Estramustine.
Why this Medication is Used
Estramustine is used to treat prostate cancer.
How do you take this Medication
Estramustine capsules are swallowed with a full glass of water, on an empty stomach (I hour before or 2 hours after eating). DO NOT open capsules. Calcium containing products (such as milk, dairy products, or antacids containing calcium) should not be taken at the same time as Estramustine.
Precautions
• Estramustine should not be used if you are trying to father a child. It is important to discuss with your doctor the possibility that this medication may cause sterility, if you plan to have children in the future. It is also important to discuss birth control methods with your doctor (Note: birth control pills alone are not recommended as the birth control method).
• Tell your doctor if you are taking any other medications. Drugs containing calcium should NOT be taken at the same time as Estramustine. Medications for high blood pressure, called ACE inhibitors (such as the medications Captopril, Enalapril, or Lisinopril) may also cause problems if taken with Estramustine.
• Tell your doctor if you have asthma, epilepsy, migraine, mental depression, blood clots, stroke, kidney disease, chickenpox, shingles, diabetes, gallbladder disease, jaundice, or stomach ulcer. Any of these conditions could affect therapy with this medication.
• If you smoke, your doctor may advise you to quit while taking Estramustine. Smoking may interact dangerously with this medication, harming your blood vessels.
• This medication may have to be taken for several months to be effective.
• Store capsules in a cool place between temperatures of 2 to 25°C (may be kept in the fridge, but do not freeze), and protected from light. Keep out of the reach of children.
For more information on this medication, please call your doctor, pharmacist or nurse.
|
SIDE EFFECTS |
PREVENTION |
WHAT YOU SHOULD DO |
|
MORE COMMON: |
||
| • Nausea and vomiting
• Diarrhea • Swelling of feet or lower legs • Breast tenderness or enlargement • Decreased interest in sex |
• Take prescribed medicine for nausea and vomiting. Continue drinking clear fluids. Get fresh air and rest. See Nausea and Vomiting pamphlet.
• Limit hot, spicy, and fried foods; limit foods and drinks with caffeine. • Avoid tight clothing • Elevate your feet when sitting |
• If you vomit within 1 hour of taking antivomiting tablets, you may take another dose. A suppository may be ordered if you can’t keep pills down. Phone your doctor if vomiting lasts more than 24 hours or nausea longer than 48 hours.
• Drink plenty of fluids. Phone your doctor if diarrhea lasts longer than 24 to 48 hours or you feel weak. • Check with your doctor as soon as possible • Tell your doctor if these become troublesome |
|
LESS COMMON: |
||
| • Trouble sleeping | • Tell your doctor if this becomes a problem | |
|
RARE: |
||
| • Vision changes
• Pains in chest, groin or leg • Skin rash or fever • Unusual tiredness • Signs of infection/ fever, chills, cough, sore throat • Low white blood cells |
• Sudden severe headache
• Weakness or numbness of the arms or legs • Limit contact with people who are sick or have colds. Rest often. Wash your hands often. |
• Call your doctor IMMEDIATELY
• Check with your doctor as soon as possible • Keep a thermometer at home. Recognize signs of infection. Phone your doctor right away if your temperature is over 38° C or 100° F. You may need antibiotics. |
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