Vitamin Supplement Reduces Prostate Cancer Incidence
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In the Journal of the National Cancer Institute (1998; 90: 440-6), researchers report that long-term supplementation with alpha-tocopherol reduced prostate cancer incidence by 32% and mortality by 41% in men who smoked. In men who took beta-carotene, cancer incidence was 23% higher and mortality 15% higher than in those receiving placebo.
In the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study, 29,133 men smokers were randomized to receive alpha-tocopherol 50 mg, beta-carotene 20 mg, both agents, or placebo for five to eight years. A total of 246 cases of prostate cancer occurred during the study, with 62 deaths.
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