Testosterone and dihydrotestosterone
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Question: How does inhibiting the conversion of testosterone to dihydrotestosterone prevent prostate growth?
Answer: The metabolite dihydrotestosterone (DHT) is the active hormone inside prostate cells, and it influences the protein synthesis within the cells. This means that the prostate must have a certain level of DHT within its cells to stimulate and maintain protein synthesis. If you lower the level of DHT inside the prostate cells, you stop or maybe even reverse the growth, since the presence of DHT is a prerequisite for the continuous growth of the gland.
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