Vitamin Supplement Reduces Prostate Cancer Incidence

Posted by admin on January 25th, 2010 No Comments

In the Journal of the National Cancer Institute (1998; 90: 440-6), researchers report that long-term supplementation with alpha-tocopherol reduced prostate cancer incidence by 32% and mortality by 41% in men who smoked. In men who took beta-carotene, cancer incidence was 23% higher and mortality 15% higher than in those receiving placebo.

In the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study, 29,133 men smokers were randomized to receive alpha-tocopherol 50 mg, beta-carotene 20 mg, both agents, or placebo for five to eight years. A total of 246 cases of prostate cancer occurred during the study, with 62 deaths.

Phytopharmaceutical Agents TABLE:Phytopharmaceutical Agents Commonly Used in Treatment of Benign Prostatic Hyperplasia Botanical Name Common Name Supposed Mechanism of Action Serenoa repens Saw palmetto • 5-alpha-reductase inhibitor • Anti-androgenic • Anti-edema • Anti-estrogenic • Anti-inflammatory • Inhibitor of prolactin and growth factors Pygeum Africanum African plum tree • Bladder desensitizer • Anti-inflammatory • Fibroblast inhibitor Urtica dioica Nettle root • 5-alpha-reductase ...
Terazosin Terazosin (Abbott's Hytrin, generics) is a long-acting, alpha1-adrenergic-receptor blocker with a prolonged half-life that permits once-daily dosing. Abbott markets terazosin in the United States and several European countries; Mitsubishi-Tokyo Pharmaceuticals is the licensee in Japan. In March 2000, the FDA granted Mylan approval ...
Review: Benign Prostatic Hypertrophy Finasteride reduced symptoms and need for surgery for benign prostatic hypertrophy. Commentator, Barry, M. Massachusetts General Hospital, Boston, MA, USA. Evidence-based Medicine, 3(4): 107, July/Aug. 1998. The following article is briefly presented The effect of finasteride on the risk of acute urinary retention and the need for ...
Opportunities for Chemoprevention Vitamin E The term "vitamin E" is used to refer to a group of naturally occurring substances that have vitamin E activity including a-, β-, δ-, and y-tocopherols (that have saturated side chains) and tocotrienols (that have unsaturated side chains). These agents have some degree ...
Benign Prostatic Hyperplasia: Alpha Blockers Overview Numerous alpha blockers have been approved for the treatment of benign prostatic hyperplasia in the major pharmaceutical markets (United States, France, Germany, Italy, Spain, United Kingdom, and Japan), largely replacing the need for surgical treatment in the past ten years. Alpha blockers, with ...

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