Cipro | Health and Prostate

Posts Tagged ‘Cipro’

Antibiotics

Posted by admin on June 21st, 2011 No Comments

Most urologists will treat prostatitis empirically with a course of antibiotics prior to receiving the results of any bacteriologic studies that are performed. Furthermore, most would continue the antibiotic for a full course (2 to 12 weeks), irrespective of the culture results. The only change, typically, would be considered if the antibiogram indicated that a particular organism was resistant to the antibiotic employed. The time course for treatment is highly variable. Most authors and research indicate that a period of 30 days is adequate but literature exists to support as long as 3 to 6 months of therapy. A number of antibiotics have been touted as the most appropriate for the treatment of classic chronic bacterial prostatitis or category II; these drugs should be used in category IIIA as well. Carbenicillin indanyl sodium (Geocillin-Roche) was probably the first antibiotic to have a specific indication for the treatment of prostatitis. It has an excellent spectrum of activity but it is cumbersome for patients as it is dosed four times a day. The tetracyclines as a group have an appropriately Read more [...]

Posted in Prostatitis

MiniDictionary

Posted by admin on October 7th, 2010 No Comments

Prostate gland A structure about the shape of a walnut that wraps around the urethra, where it exits the base of a man's bladder. The prostate gland has three lobes and produces fluid that joins the semen (which the seminal glands produce), the viscous substance that transports sperm through the man's reproductive system and out of the body during ejaculation. For reasons researchers do not understand, the prostate gland gradually enlarges with age, a condition called benign prostatic hypertrophy (BPH). An enlarged prostate gland can compress the urethra, interfering with the flow of urine. Common health conditions affecting the prostate gland include prostatitis. The prostate gland also is a common site for cancer. Prostate cancer is more common after age 60, with an increasing risk with advancing age. A physician can palpate (explore through touch) the prostate gland through digital rectal examination (DRE). DRE can permit the detection of prostate enlargement and sometimes of growths or tumors. Prostatic massage Gentle pressure applied to the prostate gland to expel accumulations of fluid, Read more [...]

Posted in Dictionary

CYPROTERONE Acetate

Posted by admin on April 30th, 2010 No Comments

CYPROTERONE Acetate (sigh-PRO-ter-own ASS-e-tate) Other Names for this Medication: Androcur, Cyprostat, Cyproteron, Procur, Cyprone, Cyprohexal, Ciproterona, Cyproteronum, Neoproxil, Siterone, Gen-cyproterone, Novo-cyproterone, Alti-CPA (Brand Names) Appearance Oral Tablets: Round, white tablets containing 50 mg of cyproterone acetate. Why this Medication is Used This medication is used for the treatment of prostate cancer. Cyproterone is an anti-testosterone (hormone) drug that slows the growth of cancer cells. It is also used to treat hot flashes. How do you take this Medication Oral Tablets: Take cyproterone as ordered by your doctor. It is better if you take the tablets by mouth after meals in 2 or 3 divided doses. Precautions • Other medications may interact with Cyproterone. Do not start taking any new medications without first checking with your doctor or pharmacist. • Tell any new doctor or dentist that you are taking Cyproterone before you receive any treatment. • If you have diabetes, you should monitor your blood sugar level closely. Cyproterone may increase Read more [...]

Posted in Drugs

Fluoroquinolone (Quinolone) antibiotics. Clinical Uses. Part 2

Posted by admin on December 4th, 2009 No Comments

Prostatitis Fluoroquinolones have been shown to penetrate into prostatic tissue in concentrations approaching or exceeding by severalfold those in serum (see preceding section). In the only comparative study, when each drug was given for 4 to 6 weeks, norfloxacin was shown to be more effective (P = 0.) than trimethoprim-sulfamethoxazole (TMP-SMX) for therapy of chronic bacterial prostatitis caused predominantly by E. coli. In two open studies also using prolonged therapy, norfloxacin and ciprofloxacin appeared to eradicate E. coli prostatitis in 85 to 92% of patients followed for at least 4 to 6 weeks after completion of therapy. Lower rates of eradication by ciprofloxacin have been associated with therapy given for only 2 weeks and with prostatitis caused by bacteria other than E. coli, including P. aeruginosa and enterococci. Pefloxacin has been reported to be effective in 21 of 31 cases (68%) of chronic prostatitis, with two of eight failures associated with the development of resistance. Acute prostatitis caused predominantly by enteric gram-negative bacilli was also cured at 7 months follow-up Read more [...]

Posted in Drugs: Antibiotics

Fluoroquinolone (Quinolone) antibiotics. Clinical Uses. Part 1

Posted by admin on December 4th, 2009 No Comments

Urinary Tract Infections Many of the newer fluoroquinolones achieve high concentrations in human urine (see preceding section). Although the antimicrobial activities of these agents are diminished in the presence of urine, urinary drug concentrations for most agents substantially exceed the minimum inhibitory concentrations (MICs) for both gram-negative and gram-positive urinary tract pathogens, including members of the Enterobacteriaceae, P. aeruginosa, enterococci, and Staphylococcus saprophyticus. Of the newer fluoroquinolones, norfloxacin and ciprofloxacin have been studied most extensively. Studies with norfloxacin and ciprofloxacin have been reviewed recently. In the two largest randomized studies of uncomplicated urinary tract infections comparing therapy with norfloxacin (400 mg given orally twice daily for 3 to 7 days) and that with trimethoprim-sulfamethoxazole (TMP-SMX), eradication of bacteriuria was significantly higher after treatment with norfloxacin in a double-blind randomized study or comparable in the two groups. Similar results were seen in a large number of other comparative Read more [...]

Posted in Drugs: Antibiotics

Diagnosis and Treatment of Prostatitis. Part 4

Posted by admin on December 2nd, 2009 No Comments

Antimicrobial Regimens for the Treatment of Acute and Chronic Bacterial Prostatitis Drug class Dose* and Route Common Side Effects Comments Trimethoprim/ sulfamethoxazole 160 mg TMP–800 mg SMX PO BID Nausea, vomiting, diarrhea, photosensitivity May be used for suppressive therapy as one single-strength tablet given once a day Fluoroquinolones ofloxacin 200 mg–400 mg PO BID Nausea, vomiting, dizziness, insomnia, photosensitivity Drug-drug interactions with theophylline, caffeine, warfarin and other drugs metabolized by the cytochrome p450 system. Drug-nutrient interactions with di– and trivalent cations (e.g., Mg, Al, Ca, Fe, Zn, and Cr) norfloxacin 400 mg PO BID ciprofloxacin 250 mg–500 mg PO BID Aminopenicillins ampicillin 2 gm IV Q6h Diarrhea, rash, hypersensitivity reactions Contraindicated in patients with a history of penicillin anaphylaxis amoxicillin 500 mg PO Q8h Aminoglycosides gentamicin 1 mg/kg–2 mg/kg Q8h Nephrotoxicity, vestibular and auditory toxicity Serum concentrations need to be Read more [...]

Posted in Prostatitis

Diagnosis and Treatment of Prostatitis. Part 2

Posted by admin on December 1st, 2009 No Comments

Acute Bacterial Prostatitis Acute bacterial prostatitis (ABP) is the least common of the prostate infections. It is usually accompanied by a urinary tract infection with positive cultures from prostatic secretions. It presents with a sudden onset of fever, chills, and low back and perianal pain. Patients often complain of obstructive (dysuria, nocturia, urgency, frequency, and burning) and irritative (hesitancy, straining, dribbling, weak stream, and incomplete emptying) urinary symptoms. Other constitutional symptoms include generalized malaise, arthralgias and myalgias. Physical examination reveals a warm, tender, swollen and indurated prostate. The diagnosis of acute bacterial prostatitis can be made based on clinical signs and symptoms. Often, urinary cultures are positive and reveal Escherichia coli as the most prevalent pathogen. Other Gram-negative microorganisms from the Enterobacteriaceae class, such as Proteus sp. and Klebsiella sp., may also be present. In patients who present with a recent history of hospitalization and/or broad-spectrum antimicrobial use, a high index of suspicion Read more [...]

Posted in Prostatitis

Posts Tagged ‘Cipro’

Symptoms and Treatment

Drugs. Meds